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Let's start with Boyd's IP Theft (oops, I mean Dictum) on Prototyping Tools: it is easier for someone who knows what they are doing to transfer a design concept on the back of a business card with a crayon than it is for someone without a clue to perform the same task with any other medium.
In other words, the important part is transferring the design concept not look at the size of my tool.
Sure, some tools make things easier. Some tools are more efficient than others.
You've got a heap of choices. Rightly or not, most client sites in Canberra are Microsoft shops, so for portability purposes there is an argument to use XP-friendly prototyping tools. I'm not saying it's right, just easier.
Some I've looked at include:
There's a lot more to prototyping tools than this - a lot more. This article is a starting place for yet another discussion on the subject.